Joshua J. Yang

Attended Discovery Day in 2016
Joshua J. Yang

What happened after high school?

After graduating high school in 2018, I pursued a degree in Molecular Biology and Immunology at the University of Toronto. During my senior year, I worked on a research project focusing on the role of a long non-coding RNA in human early embryonic development, which sparked my deeper interest in genetics. While initially considering medical school, my passion for research led me to pursue a PhD in Genetics instead. Currently, my research focuses on host antiviral factors that influence viral RNA splicing, a critical process many viruses exploit to replicate and evade human immune defences. This journey has been incredibly fulfilling, and being actively involved and recognizing the potential impact of my work continually propels me forward.

What do you remember from the Discovery Day event and what impact did it have on you?

I remember visiting a genetics laboratory during the Discovery Day event at BC Children’s Hospital and having the opportunity to load DNA into an agarose gel to separate DNA fragments by size. I was thrilled to learn about the tools that allow us to study something so nanoscopic. Aside from the hands-on experience, I also attended a workshop on how mutations in genes can contribute to cancer. The combination of practical experience and engaging discussions with researchers made me realize the real-world applications of genetic research and its potential to improve patient outcomes. Although at the time, I did not know whether I wanted to be involved in this process by becoming a physician or biomedical researcher, I was sure that I wanted to contribute to it.

Any advice for high school students?

Science begins by asking questions and seeking answers. We are witnessing a multitude of scientific publications generated every day, and there is no doubt we need more people to engage with these inquiries and contribute to finding answers. These answers are essential for exploring innovative solutions to pressing health challenges that can benefit us one day. I encourage you to ask the questions that ignite your curiosity, even if they have been addressed before. Whether you aspire to be a physician or a researcher, exploring various life science topics in post-secondary education will guide you in discovering your true passion.

About the CMHF

The Canadian Medical Hall of Fame (CMHF) celebrates Canadian heroes whose work advances health in Canada and the world, fostering future generations of health professionals through the delivery of local and national youth education programs and awards.

This enduring tribute to our country’s rich medical history is showcased here and in our physical exhibit hall in London, ON