Major influence in the field of stem cell research
Dr. Eaves’ work, spanning four decades, has provided meaningful insights into the biology of leukemia and breast cancer. Her discoveries have advanced curative therapies for patients with chronic myelogenous leukemia (CML) and identified “quiescent” CML stem cells, the first recognition of this cellular state as a hallmark of many types of chemo-resistant cancer stem cells. Dr. Eaves has also pioneered robust methods for quantifying primitive hematopoietic and mammary cells from both mice and humans that have become “gold standards” and the basis of standardized reagents with significant commercial applications. These discoveries have had profound and internationally recognized impact on bone marrow transplantation treatments for both leukemia and breast cancer.